Nice guy, but you wouldn't want his chart right now. You may know by now how I feel about progressed Mars squares. Ugh. His is to Uranus which rules television, the internet, radio, etc. It portends unexpected losses and sudden separations. Add in a stubborn adherence to misguided opinions (he's a Taurus) and you get a potential mess. Not a good time to be making a drastic change in occupations. As always with negative aspects, the less you do the better. Every action creates an opportunity for something to go wrong.
His new time slot won't work. But beyond that, this aspect creates a time in which one finds it difficult to find happiness. With Jupiter transiting in his first house, he may gain weight. With that transiting Uranus Saturn opposition that we all have somewhere in our charts, his is falling on his Venus (things he loves), his Mars (his energy) and his Moon (his feelings).
If he had had the advice of an astrologer when he was negotiating, this would not have been the time his contract ran out.
Originally blogged May 30, 2009 on Gaia.com/xtrology.
Update: Leno's ratings now that he's back at "The Tonight Show" are 1.2 to Conan's 1.1 before he got fired.